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Signs and Symptoms

Symptoms vary from mild to severe, from patient to patient, and even among family members with the disease. Symptoms are more severe in cases of early age of onset.

The first indications of CMT are mild, usually foot and ankle weakness, and fatigue. If the toes have started to curl into "claw toes," wearing shoes may become painful. Weakness in the hands also may be present.

Another sign of CMT is a highly arched foot (cavus arch). When the muscles of the foot weak...Read the full article